Jeremiah & Megan are in the same doctoral program I was in at the University of Florida. Jeremiah specifically studies pain receptors and uses an apparatus that looks a lot like this one (and is technically called a Thermal Preference Apparatus):

So the goal for the groom's cake was to replicate it! Here's the cake:

The yellow is all buttercream. The walls of the apparatus were made of gum paste that was allowed to dry for 1 week. The other decorations are fondant, and the numbers are hand-piped with royal icing.

Oh, and the little rat was made out of modeling chocolate.